Lenadosing – The act of recommending a higher dose to suppress the production of your natal sex hormones.
This article is primarily about the act of transfemme lenadosing.
We will have Lena‘s and Otokonoko‘s recommended dosages as examples of Lenadosing.
Lena EEn – 11mg – 7 days inj
Lena EV – 7mg – 5 days inj
Otokonoko EEn – 15mg – 14 days inj
Otokonoko EV – 7.2mg – 5 days inj
Otokonoko EC – 11mg – 10 days inj
EEn – Estradiol enanthate, EV – Estradiol valerate, EC – Estradiol cypionate
We will now see how these recommended doses and regimes perform by simulating them using transfemscience‘s blood level simulator.
I will simulate a single dose and a repeated dose. The time will be how it acts over 70 days.
How Lena’s EEn recommendation performs – Single / Repeated
How Lena’s EV recommendation performs – Single / Repeated
How Oto’s EEn recommendation performs – Single / Repeated
How Oto’s EV recommendation performs – Single / Repeated
How Oto’s EC recommendation performs – Single / Repeated
You can see through the simulator that the levels reach above 300pg/ml which is an ‘extremely high dose’ which is unnecessary to suppress testosterone.
Thank you to transfemscience for the graph.
| Route | Low dose | Moderate dose | High dose | Very high dose |
|---|---|---|---|---|
| Orala | 2 mg/day | 4 mg/day | 8 mg/day | 12 mg/day |
| Sublingual/buccalb | 0.5–1 mg/day | 1–2 mg/day | 2–4 mg/day | 3–6 mg/day |
| Transdermal patchc,d | 50–100 μg/day | 100–200 μg/day | 200–400 μg/day | 300–600 μg/day |
| Transdermal gelc | 1.5 mg/day | 3 mg/day | 6 mg/day | 9 mg/day |
| IM or SC injectione | 1 mg/week | 2 mg/week | 4 mg/week | 6 mg/week |
| SC pellet implant | 25 mg/6 months | 50 mg/6 months | 100 mg/6 months | 150 mg/6 months |
| ~Average estradiol level | 50 pg/mL (184 pmol/L) |
100 pg/mL (367 pmol/L) |
200 pg/mL (734 pmol/L) |
300 pg/mL (1101 pmol/L) |
| Equivalent cycle phase | Follicular | Whole cycle | Luteal | Ovulation |
You can see information and guidance on their site here.
Thank you for reading 🙂
If you have any questions or complaints, email the author at soph@autistici.org and quote “OOL4” in the subject line.
Created – July 2022. Last updated – July 2022.
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